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March 24th – Tuesday (Click to expand)
| Afternoon Session | |
| 1:00 – 4:00 pm | Registration Secretary |
| 4:00 – 4:30 pm | Welcome session Neptuno plenary Room |
| 4:30 – 5:15 pm | Opening session Chair: Anita Emmerstorfer-Augustin Decoding and designing advanced Komagataella phaffii cell factories for sustainable production of secreted proteins. Brigitte Gasser (BOKU University) |
| 5:15 – 5:45 pm | Jim Cregg tribute |
| 5:45 – 7:30 pm | Welcome Drinks & Canapés Commercial Exhibition Area |
March 25th – Wednesday (Click to expand)
| Morning Session | |
| 8:30 – 9:00 am | Breakfast coffee & sweets |
| 09:00 – 12:30 Session 1. Genetic & Synthetic Engineering of Pichia pastoris Chair: Rochelle Aw |
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| 9:00 – 9:30 am | From sterols to pigments and peptides: How K. phaffii keeps teaching us new biology Anita Emmerstorfer-Augustin (Graz University of Technology) |
9:30 – 10:00 am |
The Pichia pastoris platform for production of Nanobody® biotherapeutics |
| 10:00 – 10:20 am | ID 54. Improving effector function in Pichia-derived VHH-Fc antibodies Erhan Çıtak (VIB-UGent Center for Medical Biotechnology) |
| 10:20 – 10:40 am | ID 7. CRISPR-based tools for rational Pichia pastoris strain engineering Robert Gnuegge (Sanofi) |
| 10:40 – 11:00 am | Coffee break |
11:00 – 11:30 am |
Promoting Protein Expression in Pichia |
| 11:30 – 11:50 am | ID 16. The role of Pichia pastoris in producing Enterovirus vaccines Emma Jackson (CPI) |
| 11:50 – 12:10 pm | ID 2. Breaking Bud: Snowflake Pichia as a Living Platform for Cultivated Meat Jason Yu (Imperial College London/Bezos Centre for Sustainable Protein) |
| 12:10 – 12:30 pm | ID 53. Yeast@Zeolitic-Imidazolate-Framework Enzyme Delivery System Nina Grujicic (Graz University of Technology, NAWI Graz) |
| Afternoon Session | |
| 12:30 – 2:30 pm | Lunch & poster session |
| 14:30 – 17:10 Session 2. Host Physiology & C1-Metabolism Chair: Özge Ata |
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| 2:30 – 3:00 pm | Decoding and rewiring of Komagataella phaffii for the methanol-free production of proteins and natural products Menghao Cai (East China University of Science and Technology) |
| 3:00 – 3:20 pm | ID 15. From XuMP to RuMP in K. phaffii: the importance of compartmentalization Lisa Sanvito (BOKU University) |
| 3:20 – 3:40 pm | ID 6. Signaling pathways involved in the transcriptional response to high pH in Komagataella phaffii Joaquin Ariño (Universitat Autònoma de Barcelona) |
| 3:40 – 4:00 pm | Coffee break |
| 4:00 – 4:30 pm | Methanol utilization through native alcohol dehydrogenase improves carbon efficiency of methylotrophic yeasts Diethard Mattanovich (BOKU University) |
| 4:30 – 4:50 pm | ID 1. New development of expression system by formatotrophs K. phaffii Jianguo Zhang (University of Shanghai for Science and Technology) |
| 4:50 – 5:10 pm | ID 78. Metabolic impact of redox perturbations on recombinant protein production in Komagataella phaffii under methanolic growth conditions Eric Antón García (Universitat Autònoma de Barcelona) |
| 5:10 – 7:00 pm | Break |
| 7:00 pm | Hotel Dinner Sponsored by: |
March 26th – Thursday (Click to expand)
| Morning Session | |
| 8:30 – 9:00 am | Breakfast coffee & sweets |
| 09:00 – 12:30 Session 3. Food, Chemicals & Biopharmaceuticals Chair: Katrien Claes |
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| 9:00 – 9:30 am | Next Pichia, different strains for different products? Anton Glieder (Graz University of Technology) |
| 9:30 – 09:50 am | ID 10. High-throughput screening of therapeutic lysosomal enzymes using P. pastoris Ginevra Camboni (University of Edinburgh) |
| 09:50 – 10:10 am | ID 51. Commercial Production of Recombinant Human Lactoferrin (effera®) via a Precision Fermentation Platform in Komagataella phaffii Pamela B. Besada-Lombana (Helaina Inc) |
| 10:10 – 10:30 am | ID 21. An integrated pipeline for the discovery and recombinant production of antimicrobial macrocyclic peptides Chiara Bertaso (University of Milan) |
| 10:30 – 11:00 am | Coffee break |
| 11:00 – 11:30 am | Engineering and preclinical evaluation of dried food-formulated Pichia-secreted antibodies as peri-exposure prophylaxis against Clostridioides difficile disease Nico Callewaert (VIB-Ghent University) |
| 11:30 – 12:30 pm Flash Talks | |
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ID 3 / Panel 1. OPENPichia and Beyond: The open-access Pichia resource and VIB’s tailored N-glycoprotein production
Katrien Claes (VIB-Ghent University) ID 20 / Panel 8. Secretory expression of bovine kappa-casein in Pichia pastoris
Laura Iaria (Wageningen University) ID 22 / Panel 9. How continuous control shapes kinetic stability and lipase production in Pichia pastoris
Fuensanta Verdú (Bionet) ID 26 / Panel 13. Comparison of Feeding Strategies for Enhanced Glucose Oxidase Production in Pichia pastoris Using a Small-Scale Multi-Bioreactor System
Julia Schollmeyer (Technische Universität Berlin) ID 27 / Panel 14. Eco-friendly and high titer NANOBODY® molecule manufacturing at industrial scale
Antonov Elena (Sanofi-Aventis Deutschland GmbH) ID 28 / Panel 15. Determining feeding strategies for Komagataella phaffii
Julian Kopp-hausjell (TU Wien) ID 29 / Panel 16. Optimizing Trace Elements for Improved Protein Production in Komagataella phaffii
Marina Jecmenica (Austrian Centre of Industrial Biotechnology (ACIB)) ID 32 / Panel 17. Pichia Gold™
Knut Madden (BioGrammatics, Inc.) ID 43 / Panel 25. RapidFire-Enabled Screening of K. phaffii expression strains
Sven Heimhilcher (Bisy GmbH) ID 47 / Panel 28. Engineering a GlycoDelete Pichia pastoris Platform for Affordable Production of Site Specific Conjugates
Bo Vercauteren (VIB-Ghent University) ID 48 / Panel 29. Engineering of Pichia pastoris for Custom Glycoprotein Production
Dovilė Daunoraitė (Vilnius University) ID 49 / Panel 30. Visualizing the ER of Komagataella phaffii by Fluorescence Microscopy
Dorian Stadlmayer (BOKU University) ID 56 / Panel 31. Expression, Purification, and Proteolytic Processing of Recombinant Human Insulin from Komagataella pastoris
Vladislav Korolev (University of British Columbia) ID 61 / Panel 36. Functional characterization of the AMPK catalytic subunit in Komagataella phaffii
Asier González (Universitat Autònoma de Barcelona) ID 66 / Panel 40. Enabling fast feedback loops for protein designers through rapid progression from sequence to protein
Noah Sprent (Change Bio) |
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| Afternoon Session | |
| 12:30 – 2:30 pm | Lunch & poster session |
| 14:30 – 17:30 Session 4. Bioprocess Development & Scale-Up Chair: Xavier Garcia-Ortega |
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| 14:30 – 15:00 pm | From shaking to Artificial Intelligence: An overview of the evolution of operational strategies to maximize Komagataella phaffii Bioprocesses Francisco Valero (Universitat Autònoma de Barcelona) |
| 15:00 – 15:20 pm | ID 45. Establishing a Scalable Platform Process for VHH-Fc Antibody Manufacturing in Pichia pastoris Semiramis Yilmaz (VIB-Ghent University) |
15:20 – 15:50 pm |
Comparative Evaluation of E. coli and Pichia pastoris Expression Systems for sdAb Production |
| 15:50 – 16:20 pm | Coffee Break |
16:20 – 16:50 pm |
Accelerating Predictive Pichia Screening Using High Throughput, Controlled Microbioreactors |
| 16:50 – 17:10 pm | ID 72. Addressing strain stability to avoid reduced production efficiencies in long-term continuous cultivations Guillermo Requena-Moreno (Universitat Autònoma de Barcelona) |
| 17:10 – 17:30 pm | ID 55. Novel Komagataella phaffii expression platform for continuous cultivation Florian Weiss (Graz University of Technology) |
| 5:30 – 7:00 pm | Break |
| 7:00 pm | Official Gala Dinner at the Palma Aquarium Mallorca Sponsored by:  |
March 27th – Friday (Click to expand)
| Morning Session | |
| 8:30 – 9:00 am | Breakfast coffee & sweets |
| 09:00 – 10:30 Session 5. Beyond Fermentation Chair: Xavier Garcia-Ortega |
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| 9:00 – 9:30 am | Learning Pichia: AI/ML-Guided Strain and Process Design for Alternative Hosts Chris Love (Koch Institute at MIT) |
| 9:30 – 09:50 am | ID 50. Scaling Up Pichia fermentation: What drives colour formation in supernatant and can we control it? Chaitanyavilas Pujar (Dsm-firmenich) |
| 9:50 – 10:10 am | ID 76. Impact of Operating Conditions on TFF Performance for the Downstream Processing of Recombinant Lipase CRL1 Fuensanta Verdú-Navarro (Bioprocess Pilot Plant, Bionet) |
| 10:10 – 10:30 am | ID 35. Techno-economic insights in scaling Pichia pastoris from lab to fab Pieter De Brabander (Bio Base Europe Pilot Plant) |
| 10:30 – 11:10 am | Coffee break |
| 11:10 – 12:30 Session 6. New Challenges and Opportunities in Pichia Chair: Anita Emmerstorfer-Augustin (Sponsored by Sanofi) |
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| 11:10 – 11:40 am | Exploring in vitro glycosylation using one-pot cell-free glycoprotein synthesis with Pichia pastoris Rochelle Aw (University of Nottingham) |
| 11:40 – 12:00 pm | ID 30. Using Natural Language Processing and Large Language Models to Optimize Codon Usage for Pichia Expression Tom Chappell (BioGrammatics, Inc.) |
| 12:00 – 12:30 pm | Pichia Unchained: Automation, Glycosylation, and Beyond Karen M. Polizzi (Imperial College London) |
| 12:30 – 1:00 pm | Closing remarks & poster prizes |
| 1:00 – 2:00 pm | Picnic Lunch & Farewell |